Oxidase-like Function by Apo-Transferrin towards Manganese(III) Chelates
نویسندگان
چکیده
منابع مشابه
Quantitation of Apo - , Mono - , and Diferric Transferrin by Polyacrylamide
We have developed a polyacrylamide gradient gel electrophoretic method to quantitate apo-. mono-. and diferric transferrin based upon differences in their molecular size. Purified transferrin saturated to different extents (3% to 98%) with iron showed proportions of the three forms as predicted from an approximately random distribution of iron between the two metal-binding sites. The iron distr...
متن کاملStudy of the Binding of Iron and Indium to Human Serum Apo-Transferrin
Indium is a heavy metal belonging to group IIIa. It is believed that indium may interfere with iron metabolism from the sites of absorption, transportation, utilization and storage in the cells. The present investigation was established to study and compare the binding of iron and indium to human apo-transferrin (apo-tf). Pure human apo-tf was used and the binding activity of iron and indium, a...
متن کاملIdentification of Amino Acids Involve in Indium Binding To Serum Human Apo-Transferrin
Indium is a heavy metal belonging to group IIIa. It is used as a radioimaging and chemotherapeutic agent in diagnosis and also in the treatment of cancers. It is believed that indium may interfere with iron metabolism and reduce cell growth in cancer tissue. The present report was established to study the binding of iron and indium to apo-transferrin (apo-tf) and to identify amino acids involv...
متن کاملSingle particle reconstruction of the human apo-transferrin-transferrin receptor complex.
Most organisms depend on iron as a co-factor for proteins catalyzing redox reactions. Iron is, however, a difficult element for cells to deal with, as it is insoluble in its ferric (Fe3+) form and potentially toxic in its ferrous (Fe2+) form. Thus, in vertebrates iron is transported through the circulation bound to transferrin (Tf) and delivered to cells through an endocytotic cycle involving t...
متن کاملApo Transferrin to effect iron egress from 1 mammalian cells
Moonlighting cell surface GAPDH recruits Apo Transferrin to effect iron egress from 1 mammalian cells 2 Navdeep Sheokand, Himanshu Malhotra, Santosh Kumar , Vikas Ajit Tillu, Anoop Singh 3 Chauhan, Chaaya Iyengar Raje and Manoj Raje∗ 4 Institute of Microbial Technology, CSIR, Sector 39A, Chandigarh, INDIA-160036. 5 2 National Institute of Pharmaceutical Education & Research, Phase X, Sector 67,...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Chemistry
سال: 2012
ISSN: 1916-9701,1916-9698
DOI: 10.5539/ijc.v4n3p10